Neutrophils make up the largest fraction of white blood cells produced by the bone marrow with 100 billion cells produced daily. This amount might triple in certain conditions such as infection, inflammation, autoimmunity and cancer.
The time lapse video depicts activated neutrophils expelling NETs (rose web-like structures) into the extracellular space. Animation by Reciprocal Space www.reciprocal.space
We are developing a robust pipeline of indications that will soon transform the treatment landscape for patients with life-threatening NET–driven diseases.
Our First-In-Man study is designed to assess the safety and efficacy of therapeutic apheresis, with our NucleoCapture device in patients with sepsis and septic shock. Establishment of clinical proof of concept in sepsis and septic shock with subsequent CE Marking will position us for rapid expansion into a series of indications with unmet medical need.